Lead screws are often used in instrument grade applications where smooth, precise, clean, and maintenance free operation is required. The nut material is typically made of an internally lubricated polymer. Some examples would be laboratory and life sciences equipment such as DNA sampling, scanning and fluid handling devices. Other applications include engraving, rapid prototyping, inspection, and data storage. Lead screws are also used in heavy lifting applications when combined with a metallic (typically bronze) nut.